Apparatus

Accelerating and simplifying the development and manufacturing process of cell and gene therapies.

Medical engineers at Walter Reed National Military Medical Center are using additive manufacturing to develop customized prosthetic solutions for veterans. In fact, the center is even operating a 3D Medical Application Center (3DAC). There, a team of specialized engineers and 3D printing technicians are developing customized equipment according to the requirements of veterans.

Misconceptions about how to treat a sore throat are fuelling the overuse of antibiotics, according to STAR research.

A new approach to cancer treatment!

It is reported that researchers from Georgia Institute of Technology and Piemonte Heart Institute are using customized 3D printed heart valve models based on patients' heart CT scanning to improve the success rate of transcatheter aortic valve replacement (TAVR) surgery. Their aim is to avoid perivalvular leakage. This research has been published in JACC: Cardiovascular Imaging.

A new study shows that for a common type of skin cancer, squamous cell carcinoma of the skin, immunotherapy before surgery resulted in the complete disappearance of tumours in 50.6% of patients and more than 90% in 12.7% of patients.

A study at Massachusetts General Hospital in the US demonstrated that Adagrasib alone and in combination with cetuximab delivered good results in patients with advanced colorectal cancer with KRAS G12C mutations, with 46% of subjects experiencing substantial tumour shrinkage and an efficacy rate of 100%.

Data from a study presented at the annual meeting of the European Society of Medical Oncology in 2022 showed that lenvatinib in combination with Pembrolizumab could give 100% efficacy in this group of patients.

The US FDA has approved pemigatinib, the first targeted drug to date for patients with specific mutated blood tumours, and the results of the study show that the drug made tumours disappear completely in 79% of patients!

The FDA granted priority review status to Enhertu (DS-8201) for the treatment of patients with HR-positive, low HER2-expressing breast cancer, and Enhertu has enabled these patients to remain disease-free for an average of 10.1 months, with an average overall survival time of nearly two years. A decision on approval is expected to be made in the fourth quarter of this year.